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  • For stays longer than 90 days, please call 866-539-3446.
  • You can only book 550 days in advance.
  • Please double-check your dates.

1233 - Sheraton Clayton Plaza Hotel

Welcome to the Sheraton Clayton Plaza Hotel St. Louis, in bustling downtown Clayton. Enjoy easy access to local attractions such as the Arch, the Cardinals’ Busch Stadium, Forest Park, and the St. Louis Zoo. We are just minutes away from several Forbes and Fortune 500 business headquarters, as well as restaurants, art galleries, specialty boutiques, and shops. Step into one of our 259 inviting guest rooms and suites and escape the stresses of the day. Special touches—such as warm cherry wood furniture, High Speed Internet Access, Starbucks® coffee, and our Sheraton Signature Sleep Experience—will help you feel comfortable and relaxed.