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  • For stays longer than 90 days, please call 866-539-3446.
  • You can only book 550 days in advance.
  • Please double-check your dates.

Sheraton Clayton Plaza Hotel St. Louis

Sheraton Clayton Plaza Hotel is just minutes from St. Louis' best entertainment options, including the History Museum, Art Museum and St. Louis Zoo. In addition, we are conveniently situated in the midst of several corporate headquarters and collegiate areas including Brown Shoe, Build-A-Bear, Enterprise Rent-A-Car, Panera Bread, Centene Corporation, Spartech Corporation, Furniture Brand, Washington University, St. Louis University and Fontbonne.